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Welcome to the Rabe Research Group

The Rabe research group is a young dynamic team which is working in the area of synthetic organic chemistry, biochemistry and spectroscopy with a strong focus on time-resolved serial crystallography. Currently, we are interested in the detailed understanding of O₂ dependant reactions responsible for the generation of light, in particular those from Luciferases (responsible for one of the most visually extraordinary effect in nature – bioluminescence). We are interested in the identification of intermediates and dynamics tuning catalysis to allow this remarkable process. We are using these model enzymes to study new tools to rapidly generate O₂ for different spectroscopic methods and time-resolved crystallography experiments. Our work is very interdisciplinary and in close collaboration with Diamond Light Source. It provides excellent opportunities for students and researchers to work in a collaborative environment combining organic chemistry, chemical biology, biochemistry and cutting-edge serial crystallography and spectroscopy method development.